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INSPIRATIONS FROM HISTORY
Year : 2015  |  Volume : 20  |  Issue : 1  |  Page : 41-43

Tracing the journey of disulfiram: From an unintended discovery to a treatment option for alcoholism


Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Raman Deep Pattanayak
Department of Psychiatry, All India Institute of Medical Sciences, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-8990.164826

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Disulfiram is a drug that has been used as a deterrent agent in the treatment of alcohol use disorders. This section ventures into the journey of the discovery of the molecule, starting from the accidental discovery of its potential pathophysiological effects, thereafter becoming obscure due to lack of indications (alcohol use was not considered a problem!); and finally making a comeback and standing the rigorous test of time due to the determination of a few researchers, which makes it a story worth revisiting.


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