| REVIEW ARTICLE |
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| Year : 2019 | Volume
: 24
| Issue : 1 | Page : 4-7 |
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Insulin resistance and depression: Relationship and treatment implications
Vijender Singh1, Bhavuk Garg2
1 Department of Psychiatry, Institute of Human Behaviour and Allied Sciences, NABH Accredited Hospital Based Autonomous Institute Under Government of Delhi, Delhi, India
2 Department of Psychiatry and Drug De-Addiction Centre, Lady Hardinge Medical College and SSK Hospital, Delhi, India
Correspondence Address:
Vijender Singh
Department of Psychiatry, Institute of Human Behaviour and Allied Sciences, NABH Accredited Hospital Based Autonomous Institute Under Government of Delhi, G.T. Road, Dilshad Garden, Delhi - 110 095
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jmhhb.jmhhb_55_19
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Insulin resistance has been associated with depressive symptoms and depressive syndrome. Studies have attempted to assess the relationship between metabolic syndrome and depression and more specifically insulin resistance and depression. Studies have also been carried out to assess the direction of this relationship. This brief review is purported to present and discuss the currently available literature evidence about relationship of insulin resistance with depression and the treatment implications of this relationship. The presence of insulin resistance in an individual is positively associated with increased depressive symptoms and the presence of depressive symptoms is found to be associated with insulin resistance. However, a causal relationship could not be established. Prospective study designs can help to enhance our knowledge in finding a causal relationship. Intervention studies that will further help in treatment decisions are required.
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